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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
filingDate 1996-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f20704839d5d57603c7ecac266be7ed5
publicationDate 1999-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5876711-A
titleOfInvention Methods and compositions for determining the tumor suppressor status of cells
abstract Methods and compositions for determining the tumor suppressor status of cells are described, preferably as pertaining to the p53 status of tumor cells, and preferably in vivo using a recombinant construct consisting of a first polynucleotide sequence that encodes a reporter molecule and a second p53 binding polynucleotide sequence that is operably linked to the first polynucleotide sequence such that binding of p53 to the second polynucleotide sequence causes the expression of the reporter molecule which can be detected or quantified.
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