| abstract |
PCT No. PCT/EP95/00147 Sec. 371 Date Sep. 17, 1996 Sec. 102(e) Date Sep. 17, 1996 PCT Filed Jan. 13, 1995 PCT Pub. No. WO95/19371 PCT Pub. Date Jul. 20, 1995A host cell which is provided with a S-layer comprising a fusion polypeptide consisting essentially of: (a) at least sufficient of a S-layer protein for a S-layer composed thereof to assemble, and (b) a heterologous polypeptide which is fused to either the carboxy terminus of (a) or the amino terminus of (a) and which is thereby presented on the outer surface of the said cell; can be used as a vaccine, for screening for proteins and antigens and as a support for immobilizing an enzyme, peptide or antigen. A process of transforming B. Sphaericus cells comprising electroporation is also provided. |