http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5872281-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_241c3d4e236532a2e822eb39f56b1be9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-59 |
| filingDate | 1996-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfcc2414fc35a01be43a5759cbdc9143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b98c502fe1bb674ea7c9e843770bb503 |
| publicationDate | 1999-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5872281-A |
| titleOfInvention | Amino acid derivative having N,N-dialkylaminophenyl group |
| abstract | PCT No. PCT/JP96/00521 Sec. 371 Date Sep. 5, 1997 Sec. 102(e) Date Sep. 5, 1997 PCT Filed Mar. 5, 1996 PCT Pub. No. WO96/27585 PCT Pub. Date Sep. 12, 1996A compound of the formula <IMAGE> wherein R1 is hydrogen, lower alkyl, phenyl-lower alkyl, lower alkanoyl or benzoyl, and each phenyl in the phenyl-lower alkyl and the benzoyl is unsubstituted or substituted by halogen, lower alkyl or alkoxy; R2 represents a carboxyl or a carboxyl which is converted into an ester, an amide or a hydroxamic acid; R3 represent a lower alkyl; R4 represents a lower alkyl; A1 represents a lower alkylene which is unsubstituted or substituted by a phenyl and the phenyl is unsubstituted or substituted by halogen, lower alkyl or a lower alkoxy; A2 represents a lower alkylene; A3 represents a lower alkylene; and Z represents a sulfur or an oxygen. The compounds have inhibitory effects on LTA4 hydrolase and are useful for treating rheumatic diseases, psoriasis, inflammatory intestinal diseases, gout and cystic fibrosis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6174695-B1 |
| priorityDate | 1995-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 667.