| abstract |
Medical materials for use in treating maladies in living beings, such as ulcers and other conditions of the digestive tract. In one form, a container is provided for a medication which container also contains an adhesive material which is operatively released from the container or exposed at the surface thereof upon biodegradation or dissolution of a protective coating or wall portion of the container under the effects of fluid in the digestive tract in which the container is exposed, such as by swallowing, to permit such adhesive to temporarily bond and retain the container at a select location in the digestive tract so that it may slowly release its contents thereafter to a select portion of the digestive tract. In another form, a multitude of microcapsules, each containing a small quantity of medication, is mixed with an adhesive material, such as a sulcralfate other material which may be swallowed as a tablet or dissolved in a liquid such as water. Such microcapsules are carried with the adhesive material to be bonded temporarily therewith to a select portion of the wall of the digestive tract such that, upon biodegradation or dissolution of the walls of the capsules, the contents thereof may be released over an extended period of time to cooperate with the adhesive material in protecting the lining of the digestive tract from acids secreted by the body, food roughage and the like. |