| abstract |
This invention describes new, substituted 7 alpha -( xi -aminoalkyl)-estratrienes of general formula I <IMAGE> (I) in which side chain SK is a radical of partial formula <IMAGE> as well as their physiologically compatible addition salts with organic and inorganic acids. The new compounds represent compounds with very strong antiestrogenic action. The compounds according to the invention are, on the one hand, pure antiestrogens, or, on the other hand, antiestrogens with estrogenic partial action. Based on this spectrum of action, the new compounds are highly suitable for the production of pharmaceutical agents for tumor therapy and hormone replacement treatment. |