abstract |
New compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic activities, of the general formula: A--X 1 --NO 2 or their salts, wherein: A is R(COX u ) t , wherein t is zero or 1 and u is zero or 1; and X is O, NH or NR 1C wherein R 1C is C 1 -C 10 alkyl; and R is(Ia) wherein R 1 is acetoxoy, preferably n ortho-position with respect to --CO-- and R 2 is hydrogen; or derivatives of acetylsalylsalicyclic acid; and X 1 is --YO-- wherein Y is C 1 -C 20 alkylene, C 5 -C 7 cycloalkylene, oxy-alkyl derivatives and oxy-methyl benzyl derivatives. |