| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f731b92d51d428e777930dd67c3657f9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 |
| filingDate |
1996-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0f94bec9bb45ce504678ac627e06593
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1f3d768ccfb51f07c9231e0067a9212
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a024d3484dae1a1023a993db46c7532b |
| publicationDate |
1999-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5856111-A |
| titleOfInvention |
Methods for identifying modulators of insulin receptor phosphorylation |
| abstract |
The present invention relates to cell lines useful for the screening and identification of compounds that by modulating phosphotyrosine phosphatase activity, modulate insulin receptor type tyrosine kinase mediated signal transduction. Genetically engineered cells expressing IR in culture overcome the effect of insulin on morphology and adhesion when they are also coexpressing RPTPĪ± or RPTPĪµ. Such engineered cell lines may be used to screen and identify non-toxic compounds that could elicit or modulate insulin signal transduction even in the absence of insulin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7541151-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017064678-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7138240-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9308259-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11340238-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003182669-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003222908-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008261256-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004209308-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006188944-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7572888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03073063-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6770449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03073063-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006026702-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008004588-A1 |
| priorityDate |
1994-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |