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filingDate 1997-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e307c681f72ba5424aa9add7213ad02f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e1e43baf903503e4082b4a5f9f7a64f
publicationDate 1998-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5849476-A
titleOfInvention Recombinant varicella-zoster virus and process for constructing same
abstract The present invention provides a recombinant varicella-zoster virus prepared by inserting, into the viral genome, nucleic acids from the hepatitis B virus genome, a genomic DNA of the recombinant varicella-zoster virus, a live vaccine containing the recombinant varicella-zoster virus as an effective ingredient, an antigen derived from the recombinant varicella-zoster virus, and diagnostic agent containing the antigen. The recombinant varicella-zoster virus of the present invention can be utilized as a multivalent vaccine having an excellent immunity effect both on chicken pox and hepatitis B, and expression products and genomic DNA thereof may be used as a multivalent diagnostic agent.
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