| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a1ed4c0edbf8f456c5adca595ef3182
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_168b0644d97605cc7324a8df5a5e9a3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a26f7cda19503d5a366dc8a92a2b383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_285a635260c75f26cc101f980e629e75 |
| publicationDate |
1998-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5840494-A |
| titleOfInvention |
Method for molecular staging of prostate cancer |
| abstract |
This invention provides a method of determining the stage of prostate cancer in a human subject using a sample of peripheral blood from a human subject. The invention uses reverse transcriptase-PCR to detect the mRNA encoding prostate specific antigen (PSA) in circulating cells expressing PSA. The invention further uses digoxigenin enhancement of the resultant cDNA signal. The method has an overall sensitivity capable of detecting one PSA expressing cell per 100,000 cells. The method produced no false positives and had a superior detection selectivity for patients with nonlocalized prostate cancer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005118630-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7267956-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7547773-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6946133-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007098691-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011091498-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8178508-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241707-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008026398-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7871986-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009263425-A1 |
| priorityDate |
1994-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |