| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0023 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-015
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-14 |
| filingDate |
1996-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e98b11c15a20eecc334b71dd944663f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_764f0eab585e81d4ccc03538272bf9d7 |
| publicationDate |
1998-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5837519-A |
| titleOfInvention |
Dry-heat viral inactivation under controlled moisture conditions |
| abstract |
A method of rendering a biologically active protein composition substantially free of viruses is disclosed. The method includes the steps of preparing lyophilized samples of the protein composition having a given moisture content, determining a minimum or threshold moisture content which, when the composition is heated to pasteurizing conditions will result in at least a 3.2 log10 reduction in virus titer, and then heating the sample under pasteurizing conditions that will result in at least a 3.2 log10 reduction in virus titer while maintaining biological activity of the protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006060282-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010000111-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7755352-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11747082-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11740019-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609042-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609043-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634257-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11604026-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7816914-B1 |
| priorityDate |
1996-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |