| abstract |
This invention relates to compounds of the formula)alkoxy, amino or trifluoromethyl; and Y is -CN or -NR1R2; where l is an integer of 0, 1 or 2; m is an integer of 0, 1 or 2; n is an integer of 2, 3 or 4, except when Y is CN, in which case n can also be 1; R1 is hydrogen, (C1-C6)alkyl or (C1-C6)alkylcarbonyl; R2 is hydrogen, (C1-C10)alkylcarbonyl, (C3-C12)cycloalkylcarbonyl, hydroxy-(C1-C6)alkylcarbonyl, phenylcarbonyl, thienylcarbonyl or benzothienylcarbonyl; or R1 and R2 together with nitrogen atom to which they are attached form the ring <IMAGE> where A is C=O or CH2;and B is C=O, CHOH, CH2 or CH2CH2; and Z is halogen, hydroxy, (C1-C6)alkoxy, amino or trifluoromethyl p is 0 or 1; and pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions thereof and their use for the treatment of psychoses. |