http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5798089-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3eb62223726704e46c983cf794773f7d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D259-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D255-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D255-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D259-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-08 |
| filingDate | 1995-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb15e22f6a76f3562782e7373d4a92b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fa286a8695590339389bdfd33dc503f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8aa56dad2d8033a7f5cc81aec2b5f1a |
| publicationDate | 1998-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5798089-A |
| titleOfInvention | Chelant moieties linked to an aryl moiety by an interrupted alkylene linker |
| abstract | PCT No. PCT/GB95/00833 Sec. 371 Date Jan. 17, 1997 Sec. 102(e) Date Jan. 17, 1997 PCT Filed Apr. 12, 1995 PCT Pub. No. WO95/28392 PCT Pub. Date Oct. 26, 1995The invention provides amphiphilic compounds of the formula (I) Ch-(-L-Ar-(-AH)n)m (where Ch is a hydrophilic chelant moiety or a salt or a chelate thereof); each L is an optionally oxo substituted C2-25-alkylene linker wherein at least one CH2 moiety is replaced by a group X1 (e.g. L may include a chain sequence, an X1(CH2CH2X1)u (where u is a positive integer) such as X1(CH2CH2X1)u, CH2X1CH2CH2X1CH2CH2X1, CH2X1CH2CH2X1CH2CH2X1CH2CH2X1, etc.), and wherein L is optionally interrupted by a metabolizable group M but with the provisos that the terminus of L adjacent Ch is CH2 and that the terminus of L adjacent Ar is X1 or a CH2 group adjacent or separated by one CH2 from a group X1 (thus, for example the L-Ar linkage may be L1-X1-Ar, L1-CH2-Ar, L1-X1CH2-Ar or L1-X1CH2CH2-Ar, where L1 is the residue of L; each Ar is an aryl ring optionally substituted by or having fused thereto a further aryl ring; each AH is a protic acid group, preferably an oxyacid, e.g. a carbon, sulphur or phosphorus oxyacid or a salt thereof; each X1 is O, S, NR1 or PR1, preferably no more than 3 X1 groups being present in L; each R1 is hydrogen, alkyl or aryl; and m and n are positive integers, m being for example 1 to 4, especially 1 or 2 and n being for example, 1, 2 or 3) which are especially suited for use in diagnostic imaging of the hepatobiliary system. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6187285-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002165365-A1 |
| priorityDate | 1994-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.