http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5789423-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-56 |
| filingDate | 1996-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f62a1ded1654792407f8cb47c706ed6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31ef63e321041afce358bb2b88220942 |
| publicationDate | 1998-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5789423-A |
| titleOfInvention | 3- 5-substituted benzyl)amino!-2-phenylpiperidines as substance P antagonists |
| abstract | This invention provides a compound of the formula:ble salts, wherein R1 is C1-C6 alkyl, C3-C6 cycloalkyl, halo C1-C6 alkyl or terahydropyranyl, having one or more substituents selected from cyano, 1,3-thiazolanyl, COOR2, COR2, OCOR2, CONR3R4, NR3R4, NR5COR3 and C=CR6, wherein R2 is hydrogen or C1-C4 alkyl, R3 and R4 are independently hydrogen, C1-C4 alkyl or C3-C6 cycloalkyl, R5 is C1-C4 alkyl or C3-C6 cycloalkyl and R6 is hydrogen, halo, cyano, C1-C6 alkyl, COOH, COO(C1-C4 alkyl) or phenyl; X is C1-C6 alkoxy or halo C1-C6 alkoxy; and Ar is phenyl optionally substituted with halo. These compounds are useful in the treatment of allergic disorders, angiogenesis, gastrointestinal disorders, central nervous system disorders, inflammatory diseases, emesis, urinary incontinence, pain, migraine, sunburn, and diseases, disorders and adverse conditions caused by Helicobacter pylori, in a mammalian subject. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2015293541-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016012965-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6506775-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10154988-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10273230-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10214521-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10624875-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3610890-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227360-B2 |
| priorityDate | 1995-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 557.