Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-22 |
filingDate |
1996-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4a3190e54d6e76d73d3033ef485b757 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b367a2748e2cae3e2bb7e9d747a35d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1447641914fc7ed1a759705c20de64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee851c29a4a2952758979909a315e750 |
publicationDate |
1998-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5786472-A |
titleOfInvention |
Process for making dihydropyrimidinones |
abstract |
The present invention provides a process for forming 5-(alkyl or alkoxy)carbonyl-6-alkyl-4-(aryl or alkyl)-3,4-2(1H)-dihydropyrimidinones by combining a beta -keto ester or diketone, an aldehyde and urea in the presence of a boron reagent, a metal salt (e.g., Cu2O) and a catalyst (e.g., acid). The reaction is typically run in one pot in a solvent to afford dihydropyrimidinones in higher yields and with easier work up than previously known methods. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6320049-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101367767-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005282838-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6207444-B1 |
priorityDate |
1995-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |