| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_155ed74573c1d1438d736ceb428b6f45 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-042
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-827
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
| filingDate |
1995-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42103cc28fed028c84ba515bb2581e12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f71a250a1eb7501d603b8bdd27a5580 |
| publicationDate |
1998-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5786221-A |
| titleOfInvention |
Diagnostic test for measuring islet cell autoantibodies and reagents relating thereto |
| abstract |
An in vitro diagnostic test for analyzing body fluid so as to obtain an indication of the risk of developing insulin dependent diabetes-mellitus (IDDM) is provided. A solid phase containing immobilized pancreatic antigens is contacted with a test sample. The solid phase includes a water insoluble polymer carrier, a lectin attached to the water insoluble polymer, and mammal derived pancreatic proteins. The pancreatic proteins include pancreatic antigens which are reactive to islet cell autoantibodies which are routinely detected in the blood of patients who have recently been diagnosed as having insulin dependent diabetes mellitus (IDDM). A test sample is incubated with the solid phase containing immobilized pancreatic antigens for a sufficient time to allow a reaction between the immobilized pancreatic antigens and autoantibodies to the pancreatic antigens in the sample to bind the autoantibodies to the solid phase. Detectably labelled molecules which are selectively reactive to human IgG are then added and incubated with the solid phase for a sufficient time to allow the reaction of the labelled molecules with the bound antibodies to the pancreatic antigens to thereby attach the labelled molecules solid phase. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007141656-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10167450-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7455980-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005014200-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008187988-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006258841-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008102000-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110045126-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010143919-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009068680-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004166546-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100681503-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102008061013-A1 |
| priorityDate |
1991-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |