http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5783698-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-96 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-96 |
| filingDate | 1997-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb77a55e3893221867aa3cf674f83476 |
| publicationDate | 1998-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5783698-A |
| titleOfInvention | Chemical synthesis of 1,3-disubstituted quinazolinediones |
| abstract | The present invention relates to a method for the synthesis of 1,3-disubstituted quinazolinedione derivatives which comprises: (a) reacting a haloformate functionalized polystyrene resin with a substituted anthranilic acid derivative under conditions effective to form a urethane-linkage; (b) reacting the product of step (a) with a primary amine under conditions effective to form an anthranilamide derivative; (c) heating the anthranilamide to effect intramolecular cyclization thereby liberating the 1,3-disubstituted quinazolinedione derivative from the resin into solution; and (d) isolating the 1,3-disubstituted quinazolinedione by filtration and solvent removal. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9963939-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6429311-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9963939-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6395724-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6184377-B1 |
| priorityDate | 1996-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.