| abstract |
Disclosed is a process for preparing compounds having a straight or branched aliphatic hydrocarbon structure of formula I: <IMAGE> I In formula I, n is an integer from one to four and m is an integer from four to twenty. Independently, R1 and R2 are hydrogen, a straight or branched chain alkyl, alkenyl or alkynyl of up to twenty carbon atoms in length or -(CH2)wR5. If R1 or R2 is -(CH2)wR5, w may be an integer from one to twenty and R5 may be an hydroxyl, halo, C1-8 alkoxyl group or a substituted or unsubstituted carbocycle or heterocycle. Alternatively, R1 and R2 may jointly form a substituted or unsubstituted, saturated or unsaturated heterocycle having from four to eight carbon atoms, N being a hetero atom of the resulting heterocyle. R3 may be either hydrogen or C1-3. In the compounds, a total sum of carbon atoms comprising R1 or R2, (CH2)n and (CH2)m does not exceed forty. R4 is a terminal moiety comprising a substituted or unsubstituted, oxidized or reduced ring system, the ring system having a single ring or two to three fused rings, a ring comprising from three to seven ring atoms. The disclosed compounds are effective agents to inhibit undesirable responses to cell stimuli. |