Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e06d8df5ecb58e082a70a2bd8c474836 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 |
filingDate |
1996-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33971e79aa033544af2dba7c3cc989cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b801a8a4f3dec644068c37bad46250d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81425f138390780a5ceee86a3b90b0f9 |
publicationDate |
1998-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5770742-A |
titleOfInvention |
Thiophene-tryptamine derivatives |
abstract |
5-Thiophene-substituted tryptamine analogs are provided, which exhibit selectivity towards 5-HTD1 receptors and consequently show potential in alleviation of the symptoms of migraine. The analogs are represented by the following general chemical formula: <IMAGE> in which X represents H, C1-C4 alkyl, C1-C4 hydroxyalkyl or halogen, at the 4- or 5-position of the thiophene nucleus; Y represents a direct bond or a C1-C3 alkylene group optionally substituted with hydroxyl: and Z represents amino, mono- or di-N-lower alkyl-substituted amino, or optionally N-lower alkyl-substituted pyrrolidine. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0134146-A1 |
priorityDate |
1996-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |