| abstract |
The present invention provides a method of alleviating one or more menstrual symptoms in a woman comprising administering to said woman in need of treatment an effective amount of a compound having the formula <IMAGE> I wherein R1 and R3 are independently hydrogen, -CH3, -CO-(C1-C6 alkyl), or -CO-Ar in which Ar is optionally substituted phenyl; and R2 is selected from the group consisting of pyrrolidino, hexamethyleneimino and piperidino; or a pharmaceutically acceptable salt or solvate thereof. The present invention also provides the aforementioned method and further comprises administering to said woman an effective amount of at least one pharmaceutical agent selected from the group consisting of an analgesic, a diuretic, and an antihistamine, and compositions therefore. |