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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-12
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-12
filingDate 1996-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1998-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f59ffb2e61ee368df25c8def3818d6c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e2bca669d7741acd8a67819e038a15c
publicationDate 1998-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5756319-A
titleOfInvention Production process of S-phenyl-L-cysteine
abstract S-phenyl-L-cysteine can be produced in a high yield by reacting thiophenol and L-serine under the action of tryptophan synthase at a pH in a range of from 9.0 to 10.5. Purification of S-phenyl-L-cysteine obtained by this enzyme reaction can be effectively achieved by adjusting the pH of a crystal-containing reaction mixture to a strongly acidic level of 1.5 or lower to dissolve crystals of S-phenyl-L-cysteine, adding activated carbon to the pH-adjusted mixture, maintaining the resultant mixture at a temperature of from 20 DEG to 60 DEG C. under aeration with an oxygen-containing gas, subjecting the thus-obtained mixture to filtration, raising the pH of the resulting filtrate back to a range of from 2.5 to 6.0 to precipitate crystals of S-phenyl-L-cysteine and then recovering the thus-precipitated crystals.\!
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priorityDate 1995-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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