http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5744601-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 |
| filingDate | 1997-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1998-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f387a080a85b718ce196d2e2a45ece54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69dc683d37b7ca56a01f12e8d049fbbd |
| publicationDate | 1998-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5744601-A |
| titleOfInvention | N-(2-amino-4, 6-dichlopyrimidine-5-yl) formanide, and a process for its preparation |
| abstract | A novel pyrimidine derivative, N-(2-amino-4,6-dichloropyrimidine-5-yl)formamide for use, e.g., in the production of antiviral nucleotide derivatives, can be made by a process involving cyclyzing an aminomalonic ester with guanidine or its salt in the presence of a base to produce 2,5-diamino-4,6-dihydroxypyrimidine or its salt, chlorinating this product with a chlorinating agent in the presence of an amide to produce 4,6-dichloropyrimidine, and reacting the 4,6-dichlororpyrimidine with an aqueous solution of a carboxylic acid to produce the N-(2-amino-4,6-dichloropyrimidine-5-yl)formammide. Novel also are 4,6-dichloropyrimidine, 4,6-dichloro-N'-(dimethylamino-methylene)pyrimidine-2,5-diamine, 4,6-dichloro-N'-(piperidine-1-ylmethylene)pyrimidine-2,5-diamine, and a process for making 2,5-diamino-4,6-dichloropyrimidine. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007265287-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6433170-B1 |
| priorityDate | 1994-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.