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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485
filingDate 1996-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1998-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cedd8b064a728697d3f29d0b1ce98d3
publicationDate 1998-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5736573-A
titleOfInvention Lipid and water soluble derivatives of drugs
abstract Amine compound derivatives enhancing the transdermal delivery (skin penetration) of pharmacologically active substances (drugs). In order to pass through the skin more effectively, the present invention provides derivatives that are soluble or miscible, or compatible with both lipids and water. These derivatives are formed by combining a drug of the amine class (to which most drugs belong) with a lipid-soluble long-chain acid such as oleic, linoleic, stearic, myristic, or palmitic acid.
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