Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-627 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-946 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 |
filingDate |
1994-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2b8faa80c8a48ad64a75476d707ee16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c65f746081378094f7ee2b205d8f032 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b612015fd08844da724de34a3ba8a16f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49238d6ffe05e36c0f28f91bb101e3cb |
publicationDate |
1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5730985-A |
titleOfInvention |
Immunogens for the production of cocaine-hydrolyzing catalytic antibodies |
abstract |
Methods are described for the rapid synthesis in satisfactory yield of methyl ecgonine phenylphosphonates as analogues of transition states for the hydrolysis of the benzoyl ester of an ecgonine derivative, namely cocaine, and their linking to carrier proteins, for the purpose of using them as immunogens. The resulting immunogens elicit the formation in experimental animals of antibodies able to promote the hydrolysis of cocaine. Both these catalytic anti-cocaine antibodies and the immunogens themselves are potentially useful for the treatment of individuals seeking to avoid the pharmacological effects of cocaine and in diagnostic applications. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003069400-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10010616-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010034799-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006280735-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006280736-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011142816-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286094-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286095-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286096-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286097-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286098-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286099-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006239997-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010068222-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8318156-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8637009-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6383490-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9200265-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005124061-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006058220-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9526786-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008008358-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6017541-A |
priorityDate |
1994-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |