abstract |
A pseudobioaffinity chromatography adsorbent adapted for use in selectively adsorbing immunoglobulins. In one embodiment, the adsorbent includes: (a) a solid support material; and (b) a ligand immobilized on the surface of the solid support material, said ligand being a compound of the formula ##STR1## wherein Y 1 is selected from the group of S, SCH 3 + , O, NH, NCH 3 , CH 2 and CR 1 R 2 wherein at least one of R 1 and R 2 is not hydrogen; wherein each of Y 2 , Y 3 and Y 4 is selected from the group of N, NCH 3 + , CH, and CR wherein R is not hydrogen; and wherein at least two of Y 1 , Y 2 , Y 3 and Y 4 are neither CH 2 , CH, CR nor CR 1 R 2 . |