| abstract |
PCT No. PCT/GB94/01600 Sec. 371 Date Jan. 31, 1996 Sec. 102(e) Date Jan. 31, 1996 PCT Filed Jul. 25, 1994 PCT Pub. No. WO95/04060 PCT Pub. Date Feb. 9, 1995A compound of formula (I) is obtainable by the cultivation of a genus Streptomyces, such as Streptomyces NCIMB 40515. in the presence of rapamycin, and recovery thereof from the culture medium. The compound, and pharmaceutical compositions containing it, is useful as an immunomodulatory agent as an anticancer agent, or in the treatment of microbial infections in animals including humans. <IMAGE> (I) |