| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1096 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
1995-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cf2c6c11069a3dd25792b4825e448ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2469f56644170653bbac181d6118d61 |
| publicationDate |
1997-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5702898-A |
| titleOfInvention |
Procedure for normalization of cDNA libraries |
| abstract |
This invention provides a method to normalize a cDNA library constructed in a vector capable of being converted to single-stranded circles and capable of producing complementary nucleic acid molecules to the single-stranded circles comprising: (a) converting the cDNA library in single-stranded circles; (b) generating complementary nucleic acid molecules to the single-stranded circles; (c) hybridizing the single-stranded circles converted in step (a) with complementary nucleic acid molecules of step (b) to produce partial duplexes to an appropriate Cot; (e) separating the unhybridized single-stranded circles from the hybridized single-stranded circles, thereby generating a normalized cDNA library. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5830662-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5846721-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6372436-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008108513-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9753010-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9322014-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006257858-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6197554-B1 |
| priorityDate |
1995-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |