| abstract |
PCT No. PCT/EP94/01760 Sec. 371 Date Nov. 16, 1995 Sec. 102(e) Date Nov. 16, 1995 PCT Filed May 26, 1994 PCT Pub. No. WO94/27990 PCT Pub. Date Dec. 8, 1994Compounds of formula (I) <IMAGE> and the pharmaceutically acceptable base salts thereof, wherein R is -CO2H or tetrazol-5 yl; R1 is C3-C8alkyl optionally substituted by fluoro; and R2 is C2-C4alkyl, together with compositions containing, uses of, process for the preparation of, and intermediates used in the preparation of, such compounds. The compounds have steroid 5 alpha -reductase inhibitory activity and are useful for treating a disease such as benign prostatic hypertrophy. |