abstract |
The present invention relates to new antifungal compounds having the formula <IMAGE> wherein R1 is hydrogen, methyl, or hydroxymethyl; R2 and R3 are independently selected from the group consisting of hydrogen and C1-5 alkyl; and R4 is selected from the group consisting of beta -L-xylosyl, beta -D-ribosyl, alpha -L-arabinosyl, beta -D-chinovosyl, beta -D-fucosyl, and beta -D-glucosyl; with the proviso that when R1 is methyl or hydroxymethyl, and one of R2 or R3 is methyl, R4 is not beta -D-glucosyl; or a pharmaceutically acceptable salt thereof. |