Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd569fbfa1953ca9b7b375510e4d2763 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-967 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-811 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-579 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-579 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
filingDate |
1996-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c5832d6f451b65d1c4bb4b370911c28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79b0ba5dc05735b87e8941ae09922033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2f09e64401fcc2b9251b15febd35591 |
publicationDate |
1997-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5695948-A |
titleOfInvention |
Reagent for endotoxin assay and method for endotoxin assay using the same |
abstract |
This invention provides (1) a reagent for endotoxin assay which comprises aprotinin and a limulus amebocyte lysate reagent, (2) a kit for endotoxin assay which comprises the limulus amebocyte lysate reagent and a reagent containing aprotinin, (3) a method for assaying endotoxin in a sample using the limulus amebocyte lysate reagent in which aprotinin is added to the lysate reagent and/or the sample, (4) a method for assaying endotoxin in a serine protease-containing sample using the limulus amebocyte lysate reagent in which the sample is allowed to contact with an aprotinin-immobilized insoluble carrier in advance of endotoxin assay, (5) a carrier for pretreating a serine protease-containing sample on which aprotinin is immobilized, (6) a method for inhibiting factor G activation in which aprotinin is added to the limulus amebocyte lysate reagent and (7) a factor G activation inhibitor which comprises aprotinin as an active ingredient. Endotoxin assay can be effected based on the factor C system reaction, without influences of factor G contained in the limulus amebocyte lysate reagent and/or serine proteases contained in samples. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7867722-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1860440-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11156614-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11352656-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6391570-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1860440-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006080448-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5840510-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241788-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8440394-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7479375-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7329538-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009011448-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009286692-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7901899-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7939291-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7968280-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006183181-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008020422-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6270982-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006216780-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10119969-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10132812-B2 |
priorityDate |
1993-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |