http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5681836-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-81 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-81 |
| filingDate | 1996-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1997-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c72063c0b7ccf109cf1d35342af33d2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b2c8880ec9bd65f7864aa77b2f0f0e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9771e55f6fda3bf3610b82a6e087154e |
| publicationDate | 1997-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5681836-A |
| titleOfInvention | Methanesulfonate salts of antipsychotic benzofuran derivatives |
| abstract | The methanesulfonate salt of a class of antipsychotic compounds comprising a benzo b!furan moiety and a substituted heterocyclic moiety, linked via the 3-position of the benzo b!furan moiety by a methylene group, which are antagonists of dopamine receptor subtypes within the brain, being extremely potent antagonists of the human dopamine D 4 receptor subtype and having a selective affinity for the D 4 subtype over other dopamine receptor subtypes, possess advantageous qualities in terms of their improved aqueous solubility relative to the corresponding free base and, as such, provide for greater ease of formulation and display enhanced pharmacokinetic properties, including oral absorption. |
| priorityDate | 1995-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.