| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf9343d51902a99761e5d9ff8256b91e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
1995-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c0755a73524954b5e4ec7c04b06b869 |
| publicationDate |
1997-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5681711-A |
| titleOfInvention |
Method for promoting apoptosis in mammalian neual cells |
| abstract |
A method for determining whether a compound inhibits apoptosis induction in neural cells expressing a FALS-associated sod-1 mutant. A neural cell culture is provided having a plurality of neural cells expressing a FALS-associated sod-1 mutant, wherein through the expression of the sod-1 mutant, the neural cells have a low resistance to apoptosis induction. The neural cell culture is treated with a substance to form a modified cell culture and apoptosis is induced in the modified cell culture. The modified cell culture is then assayed to determine whether it has a higher resistance to apoptosis induction than the untreated neural cell culture. The method is useful in screening substances for use as potential drugs for treating ALS. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7393443-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006099647-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007114948-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005222046-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007008486-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7217348-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6231852-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008181872-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005069957-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007114948-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6204248-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6350467-B1 |
| priorityDate |
1995-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |