Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0dfa756d8d95385994f1521f13bdf5b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
filingDate |
1996-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d02e51f3f00f89a07a0262a39ed3132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f93cf0650a0a8cd101684407a3dc346 |
publicationDate |
1997-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5677422-A |
titleOfInvention |
Method for making a polypeptide derivative |
abstract |
A method for making a homogeneous succinylated polypeptide is disclosed. The method can be carried out by adding a succinyl-containing compound to a polypeptide solution, followed by raising the pH of the polypeptide solution to a pH of between about pH 10 to pH 12.5. The succinylation reaction between the succinyl-containing compound and free amino groups of the polypeptide is essentially complete upon raising the polypeptide solution pH to the alkaline pH. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8795724-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005053701-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9909052-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011076326-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5986050-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6770746-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004071844-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6254986-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1762574-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6017876-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003023048-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006141109-A1 |
priorityDate |
1994-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |