| abstract |
A compound of formula (I): <IMAGE> (I) in which: R1, R2, which may be identical or different, represent hydrogen or halogen, or alkyl, alkoxy, nitro or trihalomethyl, X represents CO, SO2 or CH2, A1 represents any one of the groups as defined in the description, A2 represents -(CH2)n or -CH=CH-, R3, R4, which may be identical or different, represent hydrogen or alkyl, its isomers as well as its addition salts with a pharmaceutically acceptable base and medicinal product containing the same are useful as angiogenesis inhibitors. |