Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc19d8d6ba9ad5c1fa5770341472b56 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6819 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
1991-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_567fd18c940ae1d5b4025b16c5135802 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d21a21c3c58140340a9ae563fdc568c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a7d8255b6a55bd5c2595979aa3b1154 |
publicationDate |
1997-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5670151-A |
titleOfInvention |
Method for controlling hyperproliferative diseases |
abstract |
A method for controlling the overgrowth of hyperproliferating cells in the presence of non-proliferating cells by exposing the hyperproliferating cells to a toxin conjugate that has a binding region that binds to an internalizable element of the hyperproliferating cell and a toxic moiety bound thereto is provided. The toxin conjugate may be a monoclonal antibody to transferrin receptor. Such toxin conjugates will have use in controlling hyperproliferative diseases of the integument and the eye. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6207805-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8858966-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6512096-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9173562-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011117105-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011256156-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9101695-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009053284-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9440008-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9114152-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9562230-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10138483-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006293599-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7811570-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9173732-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8377463-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006067885-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7973019-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8399653-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685434-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007259020-A1 |
priorityDate |
1986-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |