http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5648360-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-06 |
| filingDate | 1993-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1997-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90b1c4586f9e268d887e4b9a0746a705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43da53fa578743f9186bf79ea307cc01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b26b317b19fcf8d09c36214c50191e07 |
| publicationDate | 1997-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5648360-A |
| titleOfInvention | Pentacyclic antihistamines |
| abstract | PCT No. PCT/US93/04456 Sec. 371 Date Nov. 14, 1994 Sec. 102(e) Date Nov. 14, 1994 PCT Filed May 17, 1993 PCT Pub. No. WO93/23400 PCT Pub. Date Nov. 25, 1993Disclosed are novel compounds having structural formula (I) <IMAGE> (I) <IMAGE> or a pharmaceutically acceptable salt thereof, wherein X is hydrogen, halo, -CF3 or lower alkyl; Y is -(CH2)n-, wherein n is 0, 1, 2 or 3, -C(O)-, -CH2C(O)-, -CH2CH2C(O)- or -CH(OH)-; A is -N(R)- and B is -CH2-, or A is -CH2- and B is -N(R)-; R is hydrogen, lower alkyl, lower alkanoyl, -CO2R1, (a) or (b); R1 is hydrogen, lower alkyl or -CH2CCl3; and - - - - represents an optional double bond, with the proviso that the ring containing Y has only one optional double bond. Also disclosed are pharmaceutical compositions comprising these compounds and their use in treating allergy and inflammation. |
| priorityDate | 1992-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.