abstract |
The present invention describes the use of a family of fluorescent indicators for metal cations. The indicators are fluorophore conjugates of pyridyl-based metal ion chelators. The indicators are very sensitive detection as quantification reagents for a variety of metals, in a variety of oxidation states, even in the presence of high concentrations of Ca2+, Na+, or K+ or other ions, such as is found in seawater, making them highly useful for assaying physiological samples, biological samples, or environmental samples. |