abstract |
Disclosed are compounds and the pharmaceutically acceptable salts thereof useful in the diagnosis and treatment of affective disorders such as schizophrenia and depression as well as certain movement disorders such as Parkinsonism and useful in treating the extraparamidyl side effects associated with the use of conventional neuroleptic agents, which compounds have the formula: <IMAGE> where R1, X, Y and T indepedently represent inorganic or organic groups such as hydrogen, halogen, hydroxy, lower alkyl, lower alkoxy, or sulfonyl; R3 is hydrogen or lower alkyl or R3 and R4 together may form a ring structure; and R4 and R5 are the same or different and represent organic or inorganic groups where the groups may form a ring optionally substituted with various organic or inorganic substituents. |