Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
filingDate |
1994-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37fe89b0d2587bf6ff98ef8604cc8e74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f61f0685978e841a628a2609c281cbc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5418616a41d54cbb5a39c91887c8934 |
publicationDate |
1997-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5646027-A |
titleOfInvention |
Process for the production of gelatinase catalytic domain protein |
abstract |
A process for the production of the catalytic domain, without propeptide, C-terminal domain, and the fibronectin-like insert, of human gelatinases is described which comprises culturing transformed E. coli host cells carrying a synthetic DNA sequence encoding the catalytic domain as well as a method for screening for inhibitors of a gelatinase; a method for determining the 3-dimensional structure of the catalytic domain of a gelatinase; and pharmaceutical compositions of human gelatinase catalytic domain protein which are useful in treating herniated vertebral discs, dermal ulcers, modifying scar tissue formation, and joint diseases. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003099632-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8067009-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8012935-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003139345-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03033018-A1 |
priorityDate |
1994-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |