abstract |
Compositions which contain active substances and are in the form of solid particles can be obtained by intimately mixing the active substance with a water-soluble melt composed of a) 10-90% by weight of a water-soluble polymer A with a viscosity Va of 1,000-120,000 cps and b) 10-90% by weight of a water-soluble polymer B with a viscosity Vb of 1-500 cps as carrier substance, where the viscosities Va and Vb are those of a 2% by weight aqueous solution at 20 DEG C., measured by the ASTM D 2363-72 capillary method (European Pharmacopoeia, Vol. III, p. 37), and processing the melt with shaping to give the particles. |