abstract |
The present invention relates, by way of novel industrial products, to compounds which are structurally related to 15-deoxyspergualin and which have the formula <IMAGE> (I) <IMAGE> in which: A is a single bond, a group -CH2-, a group -CH2O-, a group -CH2NH-, a group -CH(OH)-, a group -CHF- or a group -CH(OCH3)-, and n is equal to 6 or 8, and their addition salts. These novel compounds are useful especially as immunosuppressants. The invention further relates to the method of preparing said compounds. |