http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5637500-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1994-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1997-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73dd74c78aee02e4b576f2f816e3b898 |
| publicationDate | 1997-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5637500-A |
| titleOfInvention | Process for preparing optically active alpha-hydroxyalkene derivatives |
| abstract | A process for preparing optically active 1-substituted-3-hydroxy-1-butene or its derivatives of formula (II) or (III) <IMAGE> (II) <IMAGE> (III) is disclosed. The process comprises treating an ester derivative of racemic 1-substituted-3-hydroxy-1-butene of formula (I), <IMAGE> (I) wherein R1 is a substituted or unsabstituted alkyl, aryl, alkoxy, or aryloxy group, and R2 is a hydrogen atom, halogen atom, an alkyl, aryl, alkoxy or aryloxy group, or a substituted or unsabstituted alkylsulfonyloxy, arylsulfonyloxy, alkylthio, or arylthio group. The process can produce a desired optically active alcohol or acyl-protected compound at a high yield and a high selectivity under mild conditions by the treatment of the substrate with a lipase. In particular, when R1=methyl and R2=halogen or phenylthio, use of Lipase AK, P-30 or K-10 gives high enantiomeric purity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8129173-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003166226-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1470220-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1470220-A2 |
| priorityDate | 1990-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.