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filingDate 1994-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1997-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1997-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5635380-A
titleOfInvention Enhancement of nucleic acid transfer by coupling virus to nucleic acid via lipids
abstract This invention provides a method of enhancing the delivery of a nucleic acid into a cell, wherein a complex is formed comprising the nucleic acid, a cationic liposome, and a replication-deficient adenovirus, and the complex is administered to the cell to thereby enhance delivery of the nucleic acid into the cell. The method can be used to deliver the nucleic acid into a cell in a subject by administering the above complex into the subject.
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