| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef2e9f5ce8630d9b282043b8d060caff |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B3-1241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B3-135 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B3-135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B3-12 |
| filingDate |
1993-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c13d9f8db67564ba4b35228b5a7a40d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ff1f9f33df8f45ba81a5a5972bfebb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8405cb0f164151b04f56a36c650d914 |
| publicationDate |
1997-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5634458-A |
| titleOfInvention |
Method for determining precorneal retention time of ophthalmic formulations |
| abstract |
Apparatus and method for measuring ophthalmic formulation retention on the surface of an eye include dissolving a fluorescent macromolecule in an ophthalmic formulation to form a fluorescently labelled formulation; topically administering the fluorescently labelled formulation to an eye, said fluorescently labelled formulation forming a thin film on the eye surface. Apparatus is provided for illuminating the eye to cause fluorescence of the fluorescently labelled formulation as the fluorescently labelled formulation thin film is eliminated from the eye by normal blinking and lacrimation; and for measuring fluorescence from the thin film as a function of time. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007089235-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6736778-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8371825-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8316477-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8205279-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007089232-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007089231-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013020917-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8313472-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6471647-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009200027-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007219511-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011046582-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007089233-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8435220-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-112008001228-T5
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6179779-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007092388-A1 |
| priorityDate |
1991-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |