| abstract |
The present invention provides immunogens for obtaining HbA1c-specific antibodies, which immunogens have the general formula: <IMAGE> (I) wherein +E,uns M+EE is 1 to 40, T is a carrier protein and A is a spacer which has a chain length of 10 to 20 atoms and has the general formula: <IMAGE> (II) wherein X is a sulphur atom or au -NH- group, +E,uns n+EE is 1 to 4 and B is an organic radical which contains a succinimide group. The present invention also provides a process for obtaining antibodies which specifically bind glycosylated haemoglobin, wherein an immunogen of general formula (I) is injected into an organism capable of antibody formation and the antibodies are then obtained in known manner. These antibodies can be used for determining HbA1c in body fluids. |