| abstract |
A method of administering to the eye a liquid ophthalmic formulation, comprising an ophthalmologically acceptable liquid and optionally containing an ophthalmologically-active substance, characterized in that the formulation has a viscosity in the range 10-3 to 1.0 Pa.s and a resistivity lower than 104 ohm.cm, and that a jet of the formulation is ejected towards the eye, from a spray nozzle situated adjacent to a piezoelectric or electromagnetic transducer, to form a stream of uniformly-sized, equally spaced, uncharged droplets, the stream of uncharged droplets is subsequently directed past a charging electrode to induce an electric charge on each droplet in the stream, and the charged droplets discharge their electric charge by earthing on contact with the eye; and spraying apparatus suitable for use in that method. |