| abstract |
PCT No. PCT/JP93/01893 Sec. 371 Date Jul. 10, 1995 Sec. 102(e) Date Jul. 10, 1995 PCT Filed Dec. 27, 1993 PCT Pub. No. WO94/15594 PCT Pub. Date Jul. 21, 1994An angiogenesis inhibitor comprising, as an active agent, Compound (I) represented by the formula below: <IMAGE> (I) where R1 is a lower alkyl group, an alkoxycarbonyl group or a carboxyl group; and R2, R3 and R4 maybe the same or different and represent a hydrogen atom, a hydroxyl group, a methoxy group or an acetoxy group. This compound has a remarkable angiogenesis inhibition activity, and an angiogenesis inhibitor useful for treatment of various diseases are provided. |