| abstract |
Novel macrolide compounds of the formula <IMAGE> (II) and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is a substituent selected from among radicals having the subformulae <IMAGE> (IIa) <IMAGE> (IIe) <IMAGE> (IIj) and <IMAGE> (IIk) and other heterocyclic radicals, as well as pharmaceutical compositions and methods of immunomodulatory treatment utilizing the same. |