| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
1994-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_204472f62d2a2627df07c709b20310e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3647fa3f7caacee78a5b531eb4496e5 |
| publicationDate |
1997-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5610286-A |
| titleOfInvention |
DNA's encoding natural killer cell enhancing factor |
| abstract |
Recombinant DNA molecules comprising a DNA sequence encoding either NKEF (Natural Killer Enhancing Factor) A or B or their amino acid sequence variants. Essentially pure natural killer enhancing factor comprising the amino acid sequence of NKEF A or B or their amino acid sequence variants. Compositions of matter for use in enhancing the activity of natural killer cells; the composition comprising an anchor moiety to which is linked either NKEF A or B or their amino acid sequence variants. Methods for enhancing the in vivo activity of natural killer cells; the methods comprising introducing in vivo a sufficient amount of either NKEF A or B or their amino acid sequence variants linked to an anchor moiety. In a method for inducing leukocyte activation and proliferation wherein the leukocytes are treated with a cytokine the improvement comprising treating the leukocytes with the cytokine in the presence of NKEF A or B or their amino acid sequence variants. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6068985-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1370697-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1370697-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7510828-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6294164-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104587463-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8563693-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6676944-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010255078-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6255079-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100818333-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004058338-A1 |
| priorityDate |
1991-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |