Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afd115dec46c157d3739020ebd4d866b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-26 |
filingDate |
1994-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e4c9b19423dbcdc2d0bdd20e5fc7c8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc3f0795ef80ee8a3715d19340da299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b5ecfacceaee874d67b1c3088d0329c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_131345d98f08f00ad388a92a4b9e9820 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dcfbd3a67e78dc8cce64d6a3a53a01d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f83edf1df85a11581a267c119581101 |
publicationDate |
1997-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5610036-A |
titleOfInvention |
Mutant AOX2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism |
abstract |
A mutant AOX2 (alcohol oxidase 2) promoter derived from the natural AOX2 promoter by base sequence deletion, insertion, or substitution is disclosed. A microbial strain carrying a gene under the control of such a mutant AOX2 promoter can be obtained by growing in a methanol-containing medium a strain incapable of producing AOX encoded by the AOX1 gene but carrying the AOX2 gene under the control of the natural AOX2 promoter. A heterologous protein may be produced by cultivating the mutant strain with the desired heterologous protein gene incorporated downstream from the mutant AOX2 promoter. A plasmid carrying the mutant AOX2 promoter is also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10105384-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-D740591-S http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1308452-C http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-501955-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011065642-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-501955-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015216891-A1 |
priorityDate |
1991-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |