Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea17ba87480b776cce77451f86b25bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff81a650b70e913d3b2524b45e4c7320 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
filingDate |
1995-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1997-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a91ba5f05c542c4b339a9636ea1a857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80b119496f3c1ccbf9763cf2bd078b2c |
publicationDate |
1997-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5599820-A |
titleOfInvention |
Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
abstract |
The present invention is directed to novel taxanes useful as chemotherapeutic agents or their precursors. Processes for preparing the novel taxanes include coupling reactions, in the presence of a base, of baccatin of formula (III) or (IV) ##STR1## with β-lactams of formula (V). ##STR2## The invention also provides pharmaceutical compositions including the novel taxanes and methods for treatment of certain cancers with these new compounds. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2289549-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6441253-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6861537-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6111144-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6075140-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6646123-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6630609-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6759431-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6545151-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2266607-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6235776-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6278026-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6235782-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6433189-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9127018-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5670658-A |
priorityDate |
1993-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |